CBI will facilitate the generation of an unique and qualitative compound library. This will be achieved by structural analysis of the available collection and assessment of chemical space coverage of compound (sub)libraries. CBI will support library enrichment and will set clear guidelines for quality, availability and uniform delivery of the compounds. A major asset of the joined chemistry effort of CBI is that chemistry follow-up for hit/lead validation will be much more enhanced than in classical screenings centers. The exact chemical expertise and background around the identified hits from the academic collection is immediately present and more derivatives of the identified hit compounds are readily available, which can quickly lead to the generation of a structure-activity relationship.
Status: library available by the end of Q2 2016